Publications

Yang SY, Monchaud D and Wong JMY. Global mapping of RNA G-quadruplexes (G4-RNAs) using G4RP-seq. Nat. Protocol. 17(3):870-889. doi: 10.1038/s41596-021-00671-6 (2022)

Yang SY, Chang EY, Lim J, Kwan HH, Monchaud D, Yip S, Stirling PC and Wong JMY.  G-quadruplexes mark alternative lengthening of telomeres.  NAR Cancer 3(3):zcab031. doi: 10.1093/narcan/zcab031. eCollection 2021 Sep.doi.org/10.1093/narcan/zcab031(2021)

Xu JL, de Oliveira DM, Trudeau MA, Chin JY, Sin D, Sandford A and Wong JMY. Mild Catalytic Defects of TERT Polymorphism rs61748181 Affect the Clinical Presentation of Chronic Obstructive Pulmonary Disease. Sci Rep 11(1):4333. doi: 10.1038/s41598-021-83686-z. (2021)

Nguyen KTTT and Wong JMY. Telomerase Biogenesis and Activities from the Perspective of Its Direct Interacting Partners. Cancers 12(6), E1679 doi: 10.3390/cancers12061679. (2020)

Thompson CAH and Wong JMY. Non-canonical Functions of Telomerase Reverse Transcriptase: Emerging Roles and Biological Relevance. Curr.Top.Med.Chem. 20(6):498-507. doi: 10.2174/1568026620666200131125110. (2020)

Renard I, Grandmougin M, Roux A, Yang SY, Lejault P, Pirrotta M, Wong JMY and Monchaud D. Small-molecule affinity capture of DNA/RNA quadruplexes and their identification in vitro and in vivo through the G4RP protocol. Nucleic Acids Res., 47(11):5502-5510 doi: 10.1093/nar/gkz215. (2019)

Yang SY, Lejault P, Chevrier S, Boidot R, Robertson AG, Wong JMY* and Monchaud D*. Transcriptome-wide identification of transient RNA G-quadruplexes in human cells. Nat Comm, 2018 Nov 9;9(1):4730. doi: 10.1038/s41467-018-07224-8. * co-senior authors

Thompson CAH, Gu A, Yang SY, Mathew V, Fleisig HB, Wong JMY.  Transient Telomerase Inhibition with Imetelstat Impacts DNA Damage Signals and Cell-Cycle Kinetics. Mol Cancer Res, 16(8):1215-1225. doi: 10.1158/1541-7786. (2018).

Grant Funding